| Catalog No. | Size | Price (USD) |
| 11031-R025-50 | 50 µL | $177.58 |
| 11031-R025-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-CD8 beta Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD8 beta |
| Immunogen | Recombinant Human CD8B / P37 / LEU2 Protein (Catalog#11031-HCCH) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD8B / P37 / LEU2 (rh CD8B / P37 / LEU2; Catalog#11031-HCCH; P10966-1; Met1-Pro170). |
| Source | Monoclonal Rabbit IgG Clone #025 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD8B1 Antibody; Anti-CD8beta Antibody; Anti-LEU2 Antibody; Anti-Ly-3 Antibody; Anti-LY3 Antibody; Anti-LYT3 Antibody; Anti-P37 Antibody
Background Information
| Full Name | CD8b molecule |
| Description | CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. P37 gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. CD8 is thought to play a role in the process of T-cell mediated killing. |
| References |
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