Anti-Adenylate Kinase 1 Antibody, Rabbit Polyclonal sinobiological 12442-RP01

$143.00
In stock
SKU
12442-RP01
Catalog No.SizePrice (USD)
12442-RP01-100100 µL$147.96
12442-RP01-200200 µL$251.64
12442-RP01-400400 µL$355.32

General Information

Product nameAnti-Adenylate Kinase 1 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman Adenylate Kinase 1
ImmunogenRecombinant Human AK1 / Adenylate kinase 1 protein (Catalog#12442-H07E)
PreparationProduced in rabbits immunized with purified, recombinant Human AK1 / Adenylate kinase 1 (rh AK1; Catalog#12442-H07E; AAH01116.1; Met1-Lys194). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-HTL-S-58j Antibody

Background Information

Full Nameadenylate kinase 1
DescriptionThe adenylate kinase (AK) isoforms network plays an important role in the intracellular energy transfer processes, the maintenance of energy homeostasis, and it is a major player in AMP metabolic signaling circuits in some highly-differentiated cells. Three other biomarkers (AK1, CLIC1, and SOD1) were significantly increased in both adenoma and early colorectal cancer patient plasma samples and in plasma from colorectal cancer mouse models at preclinical stages compared with controls.Which can contribute to the detection of early-stage colorectal cancer and adenomas.
References
  1. Lu Q, et al. (1996) Adenylate kinase complements nucleoside diphosphate kinase deficiency in nucleotide metabolism. Proc Natl Acad Sci. 93 (12): 5720-5.
  2. Dzeja P, et al. (2009) Adenylate kinase and AMP signaling networks: Metabolic monitoring, signal communication and body energy sensing. Int J Mol Sci. 10 (4): 1729-72.
  3. Lagresle-Peyrou C, et al. (2008) Human adenylate kinase 2 deficiency causes a profound hematopoietic defect associated with sensorineural deafness. Nature Genetics. 41: 106 - 11.

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