Human, Mouse, Rat Pig (Species predicted to react based on 100% sequence homology)
Immunogen
A synthetic peptide corresponding to the center region of the Human CKM / CK-MM
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human CKM / CK-MM, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
CKM, also known as CK-MM, is mainly expressed in skeletal muscle. As the primary CK isoenzyme, it also can be detected in heart muscle. CKM is a subunit of creatine kinase (CK). CK is an enzyme expressed by various tissues and cell types. It catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). In the cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type).
References
Goldblatt H. 1969, Laboratory Investigation. 21 (2): 126-8.
Hekimsoy Zeliha. et al., 2005, Endocrine Research. 31 (3): 171-5.
Döring F. et al., 2011, Scand J Med Sci Sports. 21(6):841-5.