| Catalog No. | Size | Price (USD) |
| 10501-R329-50 | 50 µL | $177.58 |
| 10501-R329-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-Carboxypeptidase B1 Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Carboxypeptidase B1 No cross-reactivity in ELISA with Mouse CPB1 Human CPA1 Human CPA2 Human CPE |
| Immunogen | Recombinant Human Carboxypeptidase B1 / CPB1 protein (Catalog#10501-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human Carboxypeptidase B1 / CPB1 (rh Carboxypeptidase B1 / CPB1; Catalog#10501-H08H; NP_001862.2; Met 1-Tyr 417). |
| Source | Monoclonal Rabbit IgG Clone #329 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CPB Antibody; Anti-PASP Antibody; Anti-PCPB Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CPB1 in human pancreas with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human Carboxypeptidase B1/CPB1 Immunohistochemistry(IHC) 18693 |
| Image 1 URL | Source image |
Background Information
| Full Name | carboxypeptidase B1 (tissue) |
| Description | Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin. |
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