Anti-DMBT1 Antibody, Rabbit Polyclonal sinobiological 11678-T16
$243.00
In stock
SKU
11678-T16
| Catalog No. | Size | Price (USD) |
| 11678-T16-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-DMBT1 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human DMBT1 |
| Immunogen | Recombinant Human DMBT1 Protein (Catalog#11678-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human DMBT1 (rh DMBT1; Catalog#11678-H08H; NP_004397.2; Met1-Ser220). DMBT1 specific IgG was purified by Human DMBT1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Gp-340 Antibody; Anti-GP340 Antibody; Anti-muclin Antibody; Anti-SAG Antibody; Anti-SALSA Antibody
Background Information
| Full Name | deleted in malignant brain tumors 1 |
| Description | Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are involved in the development of glioma (GLM). Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas , and ependymomas. DMBT1 may be considered as a candidate tumor suppressor for brain, lung, esophageal, gastric, and colorectal cancers. It may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. DMBT1 may play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. It may be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. DMBT1 may function as a binding protein in saliva for the regulation of taste sensation. It binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. |
| References |
|
title: Effects of equine SALSA on neutrophil phagocytosis and macrophage cytokine production
authors: Gary Kwok Cheong Lee; Heng Kang; ...; Angel Abuelo
journal: PLoS ONE
date: 2022-03-14
pmid: 35286327
doi: 10.1371/journal.pone.0264911
pmcid: 8920288
cited_by_count: 1
techniques: Concentration Assay; Immunoprecipitation; Incubation; Lysis; Protease Inhibitor; Purification; Spectrophotometry
bioz_score: 90
title: Salivary Scavenger and Agglutinin (SALSA) Is Expressed in Mucosal Epithelial Cells and Decreased in Bronchial Epithelium of Asthmatic Horses
authors: Gary Kwok Cheong Lee; Laurence Tessier; Dorothee Bienzle
journal: Frontiers in Veterinary Science
date: 2019-11-29
pmid: 31850379
doi: 10.3389/fvets.2019.00418
pmcid: 6896824
cited_by_count: 4
techniques: Concentration Assay; Electrophoresis; Incubation; Lysis; Protease Inhibitor; Software; Western Blot
bioz_score: 90
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