Recombinant Anti-EBAG9 Antibody, Rabbit Monoclonal sinobiological 14012-R019

$171.00
In stock
SKU
14012-R019
Catalog No.SizePrice (USD)
14012-R019-5050 µL$177.58
14012-R019-100100 µL$340.51

General Information

Product nameRecombinant Anti-EBAG9 Antibody, Rabbit Monoclonal
Validated applicationsWB (FAQ Protocol), ELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman EBAG9
ImmunogenRecombinant Human RCAS1 / EBAG9 Protein (Catalog#14012-H07E)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human RCAS1 / EBAG9 (rh RCAS1 / EBAG9; Catalog#14012-H07E; O00559; Arg28-Ser213).
SourceMonoclonal Rabbit IgG Clone #019
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-EB9 Antibody; Anti-PDAF Antibody; Anti-RCAS1 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-EBAG9 rabbit monoclonal antibody at 1:500 dilution Lane A: Hela Whole Cell Lysate Lane B: MCF7 Whole Cell Lysate Lane C: A431 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:24 kDa Observed band size:37 kDa (We are unsure as to the identity of these extra bands.)
Image 1 Alt TextHuman RCAS1 / EBAG9 Western blot (WB) 6984
Image 1 URLSource image

Background Information

Full Nameestrogen receptor binding site associated, antigen, 9
DescriptionRCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
References
  1. Ohshima K. et al., 2001, Clin Exp Immunol. 123 (3): 481-6.
  2. Ikeda K. et al., 2000, Biochem Biophys Res Commun. 273 (2): 654-60.
  3. Nakashima M. et al., 1999, Nat Med. 5 (8): 938-42.

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