| Catalog No. | Size | Price (USD) |
| 10694-RP01-100 | 100 µL | $147.96 |
| 10694-RP01-200 | 200 µL | $251.64 |
| 10694-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-EpCAM/TROP1 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human EpCAM/TROP1 |
| Immunogen | Recombinant Human EpCAM protein (Catalog#10694-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human EpCAM / TROP1 (rh EpCAM; Catalog#10694-H08H; NP_002345.1; Met 1-Lys265). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-17-1A Antibody; Anti-323/A3 Antibody; Anti-Ber-Ep4 Antibody; Anti-BerEp4 Antibody; Anti-CD326 Antibody; Anti-CO-17A Antibody; Anti-DIAR5 Antibody; Anti-EGP-2 Antibody; Anti-EGP314 Antibody; Anti-EGP34 Antibody; Anti-EGP40 Antibody; Anti-Ep-CAM Antibody; Anti-EPCAM Antibody; Anti-ESA Antibody; Anti-GA733-2 Antibody; Anti-HEA125 Antibody; Anti-HNPCC8 Antibody; Anti-KS1/4 Antibody; Anti-KSA Antibody; Anti-Ly74 Antibody; Anti-LYNCH8 Antibody; Anti-M1S2 Antibody; Anti-M4S1 Antibody; Anti-MH99 Antibody; Anti-MIC18 Antibody; Anti-MK-1 Antibody; Anti-MOC-31 Antibody; Anti-MOC31 Antibody; Anti-TACST-1 Antibody; Anti-TACSTD1 Antibody; Anti-TROP1 Antibody
Background Information
| Full Name | epithelial cell adhesion molecule |
| Description | Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway. |
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