| Catalog No. | Size | Price (USD) |
| 10188-RP01-100 | 100 µL | $147.96 |
| 10188-RP01-200 | 200 µL | $251.64 |
| 10188-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-Ephrin A3 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Ephrin A3 |
| Immunogen | Recombinant Human EphrinA3 protein (Catalog#10188-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human Ephrin-A3 (rh EphrinA3; Catalog#10188-H08H; NP_004943.1; Met 1-Ser 213). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-EFL2 Antibody; Anti-Ehk1-L Antibody; Anti-EPLG3 Antibody; Anti-LERK3 Antibody
Background Information
| Full Name | ephrin-A3 |
| Description | Ephrin-A3 also known as EPH-related receptor tyrosine kinase ligand 3 or EFNA3, is a member of the ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A3 and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: Ephrin-A3 ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A3 expressed on astrocytes activates EphA4 on the post-synaptic neuron and restricts the growth of dendritic spines through multiple pathways. |
| References |
|
title: Exogenous ephrin-A3 reverses loss of vaginal epithelial barrier protection in progestin-treated mice
authors: Mohan Liu; Rodolfo D. Vicetti Miguel; ...; Thomas L. Cherpes
journal: Mucosal immunology
date: 2025-10-01
pmid: 40571058
doi: 10.1016/j.mucimm.2025.06.007
cited_by_count: 2
techniques: Immunofluorescence; Immunohistochemistry; Incubation; Microscopy; Software; Staining
bioz_score: 93
title: Exogenous ephrin-A3 administration restores vaginal epithelial barrier function in progestin-treated mice
authors: Liu Mohan; Miguel Rodolfo D Vicetti; ...; Cherpes Thomas L
journal: bioRxiv
date: 2024-11-03
doi: 10.1101/2024.10.29.620915
cited_by_count: 0
techniques: Cream; Expressing; Genome Wide; Immunofluorescence; Immunohistochemistry; Incubation; Microscopy; Quantitative RT-PCR; Software; Staining
bioz_score: 93
