Recombinant Anti-Ezrin Antibody, Rabbit Monoclonal sinobiological 12858-R037

$171.00
In stock
SKU
12858-R037
Catalog No.SizePrice (USD)
12858-R037-5050 µL$177.58
12858-R037-100100 µL$340.51

General Information

Product nameRecombinant Anti-Ezrin Antibody, Rabbit Monoclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman Ezrin
ImmunogenRecombinant Human Ezrin / villin 2 Protein (Catalog#12858-H07E)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human Ezrin / villin 2 (rh Ezrin / villin 2; Catalog#12858-H07E; P15311; Pro2-Leu586).
SourceMonoclonal Rabbit IgG Clone #037
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CVIL Antibody; Anti-CVL Antibody; Anti-HEL-S-105 Antibody; Anti-VIL2 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human EZR in human brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Image 1 Alt TextHuman Ezrin / villin 2 Immunohistochemistry(IHC) 4215
Image 1 URLSource image

Background Information

Full Nameezrin
DescriptionVIL2, also known as villin-2, belongs to the ERM protein family. It is expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. VIL2 contains 1 FERM domain and may be involved in connections of major cytoskel
Related Pathways
  • B Cell Receptor Signaling Pathway
References
  1. Grnholm M, et al. (1999) Homotypic and heterotypic interaction of the neurofibromatosis 2 tumor suppressor protein merlin and the ERM protein ezrin. J Cell Sci. 112(6):895-904.
  2. Sitaraman, et al. (2002) The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation. J Biol Chem. 277(36):33188-95.
  3. Gould KL, et al. (1989) cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1. EMBO J. 8(13):4133-42.

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