| Catalog No. | Size | Price (USD) |
| GMP-11524-H001-1 | 1 mg | $441.37 |
| GMP-11524-H001-100 | 100 µg | $100.72 |
General Information
| Product name | Anti-CD28 Antibody |
| Validated applications | FCM (FAQ Protocol), Func/A |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD28 |
| Source | Human IgG2 Clone #H001 |
| Conjugate | Unconjugated |
| Endotoxin | < 0.5 EU/mg |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Tp44 Antibody
Image / Experimental Information
| Image 1 Description | Agonist Activity – Measured by its ability to induce proliferation of human T cells. The ED 50 for this effect is typically 0.005-0.2 ug/mL. |
| Image 1 Alt Text | Human CD28 Functional Assay (Agonist Activity) 21062 |
| Image 1 URL | Source image |
| Image 2 Description | Agonist Activity – Measured by its ability to induce proliferation of human T cells. The ED 50 for this effect is typically 0.005-0.2 ug/mL. |
| Image 2 Alt Text | Human CD28/TP44 Flow Cytometry (FC) 5569 |
| Image 2 URL | Source image |
| Image 3 Description | Agonist Activity – Measured by its ability to induce proliferation of human T cells. The ED 50 for this effect is typically 0.005-0.2 ug/mL. |
| Image 3 Alt Text | Human CD28/TP44 Flow Cytometry (FC) 5605 |
| Image 3 URL | Source image |
Background Information
| Full Name | CD28 molecule |
| Description | CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. |
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