Anti-FGF1 Antibody, Mouse Monoclonal sinobiological 10013-MM01

$143.00
In stock
SKU
10013-MM01
Catalog No.SizePrice (USD)
10013-MM01-5050 µL$147.96
10013-MM01-100100 µL$251.64
10013-MM01-200200 µL$355.32

General Information

Product nameAnti-FGF1 Antibody, Mouse Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman FGF1
ImmunogenRecombinant Human aFGF protein (Catalog#10013-HNAE)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human fibroblast growth factor acidic (rhFGF-acidic; Catalog#10013-HNAE; Phe16-Asp155; AAA79245.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SourceMonoclonal Mouse IgG1 Clone #1B7H3G2
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-AFGF Antibody; Anti-ECGF Antibody; Anti-ECGF-beta Antibody; Anti-ECGFA Antibody; Anti-ECGFB Antibody; Anti-FGF-1 Antibody; Anti-FGF-alpha Antibody; Anti-FGFA Antibody; Anti-GLIO703 Antibody; Anti-HBGF-1 Antibody; Anti-HBGF1 Antibody

Background Information

Full Namefibroblast growth factor 1 (acidic)
DescriptionaFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.
Related Pathways
  • Actin Dynamics Signaling Pathway
  • G Protein-coupled Receptors Signaling
  • MAPK-Erk Pathway
  • Autophagy Pathway
References
  1. Jaye M., et al. ,(1986), Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization. Science 233:541-545.
  2. Mergia A., et al. , (1989), Structural analysis of the gene for human acidic fibroblast growth factor.Biochem. Biophys. Res. Commun. 164:1121-1129.
  3. Wang W.P., et al. ,(1989), Cloning of the gene coding for human class 1 heparin-binding growth factor and its expression in fetal tissues.Mol. Cell. Biol. 9:2387-2395.

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