| Catalog No. | Size | Price (USD) |
| 13250-T52-50 | 50 µL | $147.96 |
| 13250-T52-100 | 100 µL | $251.64 |
| 13250-T52-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-FKBP7 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human FKBP7 |
| Immunogen | Recombinant Human FKBP7 / Rotamase protein (Catalog#13250-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human FKBP7 / Rotamase (rh FKBP7 / Rotamase; Catalog#13250-H08H; Q9Y680-2; Met1-Gln218). FKBP7 / Rotamase specific IgG was purified by Human FKBP7 / Rotamase affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-FKBP23 Antibody; Anti-PPIase Antibody; Anti-UNQ670/PRO1304 Antibody
Image / Experimental Information
| Image 1 Description | FKBP7 was immunoprecipitated using: Lane A:0.5 mg HepG2 Whole Cell Lysate Lane B:0.5 mg 293T Whole Cell Lysate 2 µL anti-FKBP7 rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-FKBP7 rabbit polyclonal antibody,at 1:200 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 26 kDa Observed band size: 26 kDa |
| Image 1 Alt Text | Human FKBP7 / Rotamase Immunoprecipitation(IP) 6052 |
| Image 1 URL | Source image |
| Image 2 Description | FKBP7 was immunoprecipitated using: Lane A:0.5 mg HepG2 Whole Cell Lysate Lane B:0.5 mg 293T Whole Cell Lysate 2 µL anti-FKBP7 rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-FKBP7 rabbit polyclonal antibody,at 1:200 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 26 kDa Observed band size: 26 kDa |
| Image 2 Alt Text | Human FKBP7 / Rotamase Western blot (WB) 6685 |
| Image 2 URL | Source image |
Background Information
| Full Name | FK506 binding protein 7 |
| Description | PPIase is a member of the immunophilin protein family. It also belongs to the cyclophilin-type PPIase family, PPIL3 subfamily. PPIase contains 1 PPIase cyclophilin-type domain. Members of the immunophilin protein family play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It has a very high substrate specificity for the four-residue peptide Ala-Ala-Pro-Phe only when the proline peptide bond is in the trans state. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. |
| References |
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