| Catalog No. | Size | Price (USD) |
| 103115-T32-50 | 50 µL | $147.96 |
| 103115-T32-100 | 100 µL | $251.64 |
| 103115-T32-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-GFRAL Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human GFRAL |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human GFRAL |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human GFRAL, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-bA360D14.1 Antibody; Anti-C6orf144 Antibody; Anti-GRAL Antibody; Anti-UNQ9356 Antibody; Anti-UNQ9356/PRO34128 Antibody
Image / Experimental Information
| Image 1 Description | Anti-GFRAL rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:45 kDa Observed band size:45 kDa |
| Image 1 Alt Text | Human GFRAL Western blot (WB) 15450 |
| Image 1 URL | Source image |
Background Information
| Description | Macrophage inhibitory cytokine-1/growth differentiation factor 15 (MIC-1/GDF15) is a divergent transforming growth factor (TGFbeta) superfamily cytokine implicated in biological and disease processes including metabolism, cancer, and chronic inflammation. GDNF family receptor alpha-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. |
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