Recombinant Anti-GOLPH2/GOLM1 Antibody, Rabbit Monoclonal sinobiological 13066-R024

$171.00
In stock
SKU
13066-R024
Catalog No.SizePrice (USD)
13066-R024-5050 µL$177.58
13066-R024-100100 µL$340.51

General Information

Product nameRecombinant Anti-GOLPH2/GOLM1 Antibody, Rabbit Monoclonal
Validated applicationsELISA (FAQ Protocol), FCM (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman GOLPH2/GOLM1
ImmunogenRecombinant Human GOLM1 / GP73 protein (Catalog#13066-H08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human GOLM1 (rh GOLM1; Catalog#13066-H08H; Q8NBJ4-1; Val 40-Leu 401).
SourceMonoclonal Rabbit IgG Clone #024
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-bA379P1.3 Antibody; Anti-C9orf155 Antibody; Anti-FLJ23608 Antibody; Anti-GOLPH2 Antibody; Anti-GP73 Antibody; Anti-HEL46 Antibody; Anti-PSEC0242 Antibody; Anti-PSEC0257 Antibody; Anti-UNQ686/PRO1326 Antibody

Image / Experimental Information

Image 1 DescriptionFlow cytometric analysis of Human GOLM1(GP73) expression on HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human GOLM1(GP73), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Image 1 Alt TextHuman GOLPH2 Flow Cytometry (FC) 19133
Image 1 URLSource image

Background Information

Full Namegolgi membrane protein 1
DescriptionGolgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2, and GOLM1, is a protein that belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in the colon, prostate, trachea, and stomach. It is expressed at a lower level in testis, muscle, lymphoid tissues, white blood cells, and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at a low level in the normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncytial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.
References
  1. Kladney R.D., et al. ,(2000), GP73, a novel Golgi-localized protein upregulated by viral infection. Gene 249:53-65.
  2. Clark H.F., et al. , (2003), The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.Genome Res. 13:2265-2270.
  3. Puri S., et al. ,(2002), Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption.Traffic 3:641-653.

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