Recombinant Human GSTM2 protein (Catalog#12042-H07E)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human GSTM2 (rh GSTM2; Catalog#12042-H07E; P28161; Met1-Lys218).
Source
Monoclonal Rabbit IgG Clone #005
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta. Butyrate, an important luminal component produced from the fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotective by increasing detoxification capabilities in the colon mucosa.
References
Campbell E, et al.,1990, J Biol Chem 265 (16): 9188-93.
Vorachek WR, et al.,1991, Proc Natl Acad Sci USA. 88 (10): 4443-7.
Ebert,M.N. et al., 2003, Carcinogenesis. 24 (10):1637-44.