Recombinant Anti-GSTM2 Antibody, Rabbit Monoclonal sinobiological 12042-R005

$171.00
In stock
SKU
12042-R005
Catalog No.SizePrice (USD)
12042-R005-5050 µL$177.58
12042-R005-100100 µL$340.51

General Information

Product nameRecombinant Anti-GSTM2 Antibody, Rabbit Monoclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman GSTM2
ImmunogenRecombinant Human GSTM2 protein (Catalog#12042-H07E)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human GSTM2 (rh GSTM2; Catalog#12042-H07E; P28161; Met1-Lys218).
SourceMonoclonal Rabbit IgG Clone #005
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-GST4 Antibody; Anti-GSTM Antibody; Anti-GSTM2-2 Antibody; Anti-GTHMUS Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human GSTM2 in human leiomyoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Image 1 Alt TextHuman GSTM2 Immunohistochemistry(IHC) 4084
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human GSTM2 in human leiomyoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Image 2 Alt TextHuman GSTM2 Immunohistochemistry(IHC) 4085
Image 2 URLSource image
Image 3 DescriptionImmunochemical staining of human GSTM2 in human leiomyoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Image 3 Alt TextHuman GSTM2 Immunohistochemistry(IHC) 4086
Image 3 URLSource image

Background Information

Full Nameglutathione S-transferase mu 2 (muscle)
DescriptionGlutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta. Butyrate, an important luminal component produced from the fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotective by increasing detoxification capabilities in the colon mucosa.
References
  1. Campbell E, et al.,1990, J Biol Chem 265 (16): 9188-93.
  2. Vorachek WR, et al.,1991, Proc Natl Acad Sci USA. 88 (10): 4443-7.
  3. Ebert,M.N. et al., 2003, Carcinogenesis. 24 (10):1637-44.

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