| Catalog No. | Size | Price (USD) |
| 105099-T08-50 | 50 µL | $147.96 |
| 105099-T08-100 | 100 µL | $251.64 |
| 105099-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-HDAC6 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human HDAC6 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human HDAC6 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human HDAC6, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CPBHM Antibody; Anti-FLJ16239 Antibody; Anti-HD6 Antibody; Anti-HDAC6 Antibody; Anti-JM21 Antibody; Anti-KDAC6 Antibody; Anti-KIAA0901 Antibody; Anti-PPP1R90 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human HDAC6 in human testis with rabbit polyclonal antibody at 1:250 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human HDAC6 Immunohistochemistry(IHC) 18285 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human HDAC6 in human testis with rabbit polyclonal antibody at 1:250 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human HDAC6 Immunohistochemistry(IHC) 18286 |
| Image 2 URL | Source image |
Background Information
| Description | Histone deacetylase 6 (HDAC6) is a microtubule-associated deacetylase whose function includes regulation of α-tubulin-dependent intracellular mitochondrial transport. HDAC6 is involved in cell motility, cell survival, cell cycle progression, developmental events, prognosis as well as protein degradation. HDAC6 was first discovered in 1999 because of its homology to HDAC1. The gene encoding HDAC6 is localized to the sub-band border of chromosome Xp11.22-23 in humans. Unlike most HDAC isoforms, HDAC6 contains a Ser Glu-repeat domain (SE14) that acts as a cytoplasmic retention signal and mediates its stable anchorage in the cytoplasm. HDAC6 has emerged as a promising target for the treatment of various human diseases including cancer, neurodegenerative disease and immunology due to its unique structure, substrate and biological functions. |
| References |
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