| Catalog No. | Size | Price (USD) |
| 10368-RP02-50 | 50 µL | $147.96 |
| 10368-RP02-100 | 100 µL | $251.64 |
| 10368-RP02-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-IL-33 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IL-33 |
| Immunogen | Recombinant Human IL-33 protein (Catalog#10368-HNAE) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human IL-33 (rh IL-33; Catalog#10368-HNAE; Ser 112-Thr 270; NP_254274.1). IL-33 specific IgG was purified by human IL-33 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-C9orf26 Antibody; Anti-DKFZp586H0523 Antibody; Anti-DVS27 Antibody; Anti-IL1F11 Antibody; Anti-NF-HEV Antibody; Anti-NFEHEV Antibody; Anti-NFHEV Antibody
Image / Experimental Information
| Image 1 Description | Anti-IL33 rabbit polyclonal antibody at 1:500 dilution Lane A: K562 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:31 kDa Observed band size:39 kDa (We are unsure as to the identity of these extra bands.) |
| Image 1 Alt Text | Human IL-33 Western blot (WB) 13204 |
| Image 1 URL | Source image |
Background Information
| Full Name | interleukin 33 |
| Description | Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders. |
| Related Pathways |
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| References |
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title: Interleukin-33 Promotes Cell Survival via p38 MAPK-Mediated Interleukin-6 Gene Expression and Release in Pediatric AML
authors: Yiqian Wang; Haibo Su; ...; Qing Gong
journal: Frontiers in Immunology
date: 2020-11-26
pmid: 33324412
doi: 10.3389/fimmu.2020.595053
pmcid: 7726021
cited_by_count: 9
techniques: Cell Culture; Enzyme-linked Immunosorbent Assay; Expressing; In Vitro; Incubation; Real-time Polymerase Chain Reaction; Staining; Western Blot
bioz_score: 90
