| Catalog No. | Size | Price (USD) |
| 100928-T34-50 | 50 µL | $147.96 |
| 100928-T34-100 | 100 µL | $251.64 |
| 100928-T34-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-KAT1/HAT1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Mouse, Rat (Species predicted to react based on 100% sequence homology) |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human HAT1 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human HAT1, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-KAT1 Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of HAT1 in HeLa cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human HAT1 polyclonal antibody (1:1000) at 4℃ overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to nucleus. |
| Image 1 Alt Text | Human HAT1 Immunofluorescence(IF) 3034 |
| Image 1 URL | Source image |
| Image 2 Description | Immunofluorescence staining of HAT1 in HeLa cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human HAT1 polyclonal antibody (1:1000) at 4℃ overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to nucleus. |
| Image 2 Alt Text | Human HAT1 Western blot (WB) 6534 |
| Image 2 URL | Source image |
Background Information
| Full Name | histone acetyltransferase 1 |
| Description | HAT1 (Histone Acetyltransferase 1) is a Protein Coding gene. The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. HAT1 can up-regulate cell apoptosis. The dysfunction of apoptosis is one of the factors contributing to lung cancer (LC) growth. Upregulation of HAT1 expression in LCCs can induce LCCs apoptosis, which may be a potential novel therapy for the treatment of LC. KAT8 or HAT1 regulate HBV replication and may be potential drug targets of anti-HBV therapy. HAT1 played an important role in esophageal carcinoma and that it could be a novel EC therapeutic target. |
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