Anti-ILT11/LILRA5/LIR-9 Antibody, Rabbit Polyclonal sinobiological 16059-T16

$143.00
In stock
SKU
16059-T16
Catalog No.SizePrice (USD)
16059-T16-5050 µL$147.96
16059-T16-100100 µL$251.64
16059-T16-200200 µL$355.32

General Information

Product nameAnti-ILT11/LILRA5/LIR-9 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman ILT11/LILRA5/LIR-9
ImmunogenRecombinant Human LILRA5 Protein (Catalog#16059-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human LILRA5 (rh LILRA5; Catalog#16059-H08H; NP_067073.1; Met1-Arg268). LILRA5 specific IgG was purified by Human LILRA5 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CD85 Antibody; Anti-CD85F Antibody; Anti-ILT-11 Antibody; Anti-ILT11 Antibody; Anti-LILRB7 Antibody; Anti-LIR-9 Antibody; Anti-LIR9 Antibody

Background Information

Full Nameleukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
DescriptionLILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs, and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node, and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.
Research Areas
  • ITIM/ITAM Immunoreceptors and Related Molecules
References
  1. Wende H, et al. (2000) Extensive gene duplications and a large inversion characterize the human leukocyte receptor cluster. Immunogenetics. 51(8-9):703-13.
  2. Jones DC, et al. (2009) Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes. Eur J Immunol. 39(11):3195-206.
  3. Mosbruger TL, et al. (2010) Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. J Infect Dis. 201(9):1371-80.

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