| Catalog No. | Size | Price (USD) |
| 102715-T08-50 | 50 µL | $147.96 |
| 102715-T08-100 | 100 µL | $251.64 |
| 102715-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-MCT1/MCTS1 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human, Mouse, Rat |
| Specificity | Human, Mouse, Rat |
| Immunogen | A synthetic peptide corresponding to the center region of the Human MCTS1 / Malignant T cell amplified sequence 1 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human MCTS1 / Malignant T cell amplified sequence 1, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-IMD118 Antibody; Anti-MCT-1 Antibody; Anti-MCT1 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining MCTS1 in human pancreas with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Human MCTS1/Malignant T cell amplified sequence 1 Immunohistochemistry(IHC) 3902 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining MCTS1 in human pancreas with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Image 2 Alt Text | Human MCTS1/Malignant T cell amplified sequence 1 Immunohistochemistry(IHC) 17972 |
| Image 2 URL | Source image |
| Image 3 Description | Immunochemical staining MCTS1 in human pancreas with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Image 3 Alt Text | Human MCTS1/Malignant T cell amplified sequence 1 Immunohistochemistry(IHC) 17982 |
| Image 3 URL | Source image |
Background Information
| Full Name | malignant T cell amplified sequence 1 |
| Description | MCTS1 (MCTS1 Re-Initiation And Release Factor) is a Protein Coding gene. The encoded protein belongs to the MCTS1 family. Density-regulated reinitiation and release factor (DENR) and multiple copies in T-cell lymphoma-1 (MCTS1) are implicated in promoting translation reinitiation both in vitro in translation extracts and in vivo. The crystal structure of MCTS1 is bound to a fragment of DENR. Since DENR-MCTS1 can bind tRNA in the absence of the ribosome, this suggests the DENR-MCTS1 complex could recruit tRNA to the ribosome during reinitiation analogously to the eukaryotic initiation factor 2 (eIF2) complex in cap-dependent translation. MCTS1 is widely expressed in the lymph node, brain, and other tissues. Diseases associated with MCTS1 include Lymphoma. |
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