| Catalog No. | Size | Price (USD) |
| 104345-T32-50 | 50 µL | $147.96 |
| 104345-T32-100 | 100 µL | $251.64 |
| 104345-T32-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-NAA50 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Mouse (Species predicted to react based on 100% sequence homology) |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human NAA50 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human NAA50, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-FLJ13194 Antibody; Anti-hNaa50p Antibody; Anti-MAK3 Antibody; Anti-NAT13 Antibody; Anti-NAT13P Antibody; Anti-NAT5 Antibody; Anti-NAT5P Antibody; Anti-SAN Antibody
Image / Experimental Information
| Image 1 Description | Anti-NAA50 rabbit polyclonal antibody at 1:500 dilution Lane A: K562 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:19 kDa Observed band size:19 kDa |
| Image 1 Alt Text | Human NAA50 Western blot (WB) 19838 |
| Image 1 URL | Source image |
Background Information
| Full Name | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| Description | Naa50 (also known as San) has previously been shown to play a role in sister-chromatid cohesion in metazoans. The gene separation anxiety (san) encodes Naa50/San, an N-terminal acetyltransferase required for chromosome segregation during mitosis. Naa50/San N-terminally acetylates the nascent Scc1 polypeptide, and that this co-translational modification is subsequently required for the establishment and/or maintenance of sister chromatid cohesion. NAA50, an interactor of EDR1, plays an important role in regulating the tradeoff between plant growth and defense. Plants lacking NAA50 display severe developmental defects as well as induced stress responses. Reduction of NAA50 expression results in arrested stem and root growth as well as senescence. The loss of NAA50 results in constitutive ER stress signaling, indicating that NAA50 may be required for the suppression of ER stress. |
| References |
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