| Catalog No. | Size | Price (USD) |
| 111172-R0049-20 | 20 µL | $103.53 |
| 111172-R0049-100 | 100 µL | $296.07 |
General Information
| Product name | Phospho-PKCα (Thr638) Antibody, Rabbit MAb |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human Predicted to React with: > Human Phospho-PKCα (Thr638) Predicted to React with: Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Bovine |
| Specificity | Reacts with: Human Human Phospho-PKCα (Thr638) Predicted to React with: Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Bovine |
| Immunogen | A synthetic phosphopeptide corresponding to residues around Thr638 of human Phospho-PKCα. |
| Preparation | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Thr638 of human Phospho-PKCα. |
| Source | Monoclonal Rabbit IgG Clone #0049 |
| Purification | Protein A |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AAG6 Antibody; Anti-PKC-alpha Antibody; Anti-PKCA Antibody; Anti-PKCalpha Antibody; Anti-PKCI+/- Antibody; Anti-PKCα Antibody; Anti-PRKACA Antibody
Image / Experimental Information
| Image 1 Description | Western blot analysis of extracts from HEK-293, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-PKCα (Thr638) Antibody, Rabbit MAb (Cat: 111172-R0049) at 1:1000 dilution. |
| Image 1 Alt Text | Human PKC alpha/PRKCA Western blot (WB) 42338 |
| Image 1 URL | Source image |
| Image 2 Description | Western blot analysis of extracts from HEK-293, untreated (line A); treated with antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-PKCα (Thr638) Antibody, Rabbit MAb (Cat: 111172-R0049) at 1:1000 dilution. |
| Image 2 Alt Text | Human PKC alpha/PRKCA Western blot (WB) 42339 |
| Image 2 URL | Source image |
Background Information
| Full Name | protein kinase C, alpha |
| Description | Protein kinase C alpha (PRKCA) is involved in multiple functions and has been implicated in heart failure risks and treatment outcomes. The protein kinase C alpha (PRKCA) gene, coding for a Th17-cell-selective kinase, shows a complex splicing pattern, with at least 2 stable alternative transcripts characterized by an alternative upstream polyadenylation site. Polymorphisms in this gene were associated with several conditions, including multiple sclerosis, asthma, schizophrenia, and cancer. The protein kinase C alpha (PRKCA) gene, encoding a Th17-cell-selective kinase, was repeatedly associated with multiple sclerosis (MS).PRKCA polymorphisms and gene-gene interactions within the ACEi pathway affect the antihypertensive responses to enalapril. |
| Related Pathways |
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