Anti-Activin A Antibody, Rabbit Polyclonal sinobiological 10429-T16
$243.00
In stock
SKU
10429-T16
| Catalog No. | Size | Price (USD) |
| 10429-T16-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-Activin A Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human, Mouse, Rat, Cynomolgus, Rhesus |
| Specificity | Human, Mouse, Rat, Cynomolgus, Rhesus Activin A |
| Immunogen | Recombinant Human, Mouse, Rat, Cynomolgus, Rhesus Activin A Protein (Catalog#10429-HNAH) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human, Mouse, Rat, Cynomolgus, Rhesus Activin A (Catalog#10429-HNAH; NP_002183.1; Gly311-Ser426). Activin A specific IgG was purified by Human, Mouse, Rat, Cynomolgus, Rhesus Activin A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Background Information
| Full Name | inhibin, beta A |
| Description | Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two monomers are linked to one another by a single disulfide bond. Activin is composed of two β subunits, βA βA (activin A), βB βB (activin B), or βA βB (activin AB). Inhibin is composed of an alpha and one of two β subunits, βA (inhibin A) or βB (inhibin B). Activins are produced in many cell types and organs, such as gonads, pituitary gland, and placenta. In the ovarian follicle, activin increases FSH binding and FSH-induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male, activin enhances spermatogenesis. Also, Activin plays a role in wound repair and skin morphogenesis. Activin is strongly expressed in wounded skin, and overexpression of activin in the epidermis of transgenic mice improves wound healing and enhances scar formation. Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and kidney. There is also evidence showed that lack of activin during development results in neural developmental defects. |
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