| Catalog No. | Size | Price (USD) |
| 10354-MM11-1 | 1 mL | $1,377.43 |
| 10354-MM11-20 | 20 µL | $88.87 |
| 10354-MM11-50 | 50 µL | $147.96 |
| 10354-MM11-100 | 100 µL | $251.64 |
| 10354-MM11-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-RBP4 Antibody, Mouse Monoclonal |
| Validated applications | ELISA(Cap) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human RBP4 |
| Immunogen | Recombinant Human RBP4 Protein (Catalog#10354-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RBP4 (rh RBP4; Catalog#10354-H08H; NP_006735.2; Met1-Leu201). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #11 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-MCOPCB10 Antibody; Anti-PRO2222 Antibody; Anti-RDCCAS Antibody
Background Information
| Full Name | retinol binding protein 4, plasma |
| Description | Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). |
| References |
|
