| Catalog No. | Size | Price (USD) |
| 11186-MM01-1 | 1 mL | $1,377.43 |
| 11186-MM01-20 | 20 µL | $88.87 |
| 11186-MM01-50 | 50 µL | $147.96 |
| 11186-MM01-100 | 100 µL | $251.64 |
| 11186-MM01-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-REG4 Antibody, Mouse Monoclonal |
| Validated applications | ELISA(Det) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human REG4 |
| Immunogen | Recombinant Human REG4 Protein (Catalog#11186-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human REG4 (rh REG4; Catalog#11186-H08H; NP_001152824.1; Met1-Pro158). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #01 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-GISP Antibody; Anti-REG-IV Antibody; Anti-RELP Antibody
Background Information
| Full Name | regenerating islet-derived family, member 4 |
| Description | Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution. |
| References |
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