| Catalog No. | Size | Price (USD) |
| 10105-RP03-50 | 50 µL | $147.96 |
| 10105-RP03-100 | 100 µL | $251.64 |
| 10105-RP03-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-ST2/IL-1 RL1 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ST2/IL-1 RL1 |
| Immunogen | Recombinant Human IL1RL1 protein (Catalog#10105-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human IL1RL1 extracellular domain (rhIL1RL1; Catalog#10105-H08H; Met1-Phe328; NP_003847.2). IL1RL1 specific IgG was purified by human IL1RL1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-DER4 Antibody; Anti-FIT-1 Antibody; Anti-IL33R Antibody; Anti-ST2 Antibody; Anti-ST2L Antibody; Anti-ST2V Antibody; Anti-T1 Antibody
Background Information
| Full Name | interleukin 1 receptor-like 1 |
| Description | IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines. |
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