| Catalog No. | Size | Price (USD) |
| 12735-MM04-1 | 1 mL | $1,377.43 |
| 12735-MM04-20 | 20 µL | $88.87 |
| 12735-MM04-50 | 50 µL | $147.96 |
| 12735-MM04-100 | 100 µL | $251.64 |
| 12735-MM04-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Tetranectin/CLEC3B Antibody, Mouse Monoclonal |
| Validated applications | ELISA(Cap) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Tetranectin/CLEC3B |
| Immunogen | Recombinant Human Tetranectin / CLEC3B Protein (Catalog#12735-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Tetranectin / CLEC3B (rh Tetranectin / CLEC3B; Catalog#12735-H08H; AAX37102.1; Met1-Val202). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG2b Clone #04 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-MCDR4 Antibody; Anti-TN Antibody; Anti-TNA Antibody
Background Information
| Full Name | C-type lectin domain family 3, member B |
| Description | Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize. |
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