Anti-IL-1 beta Antibody, Rabbit Polyclonal sinobiological 70018-T16

$243.00
In stock
SKU
70018-T16
Catalog No.SizePrice (USD)
70018-T16-100100 µL$251.64

General Information

Product nameAnti-IL-1 beta Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Canine
SpecificityCanine IL-1 beta
ImmunogenRecombinant Canine IL-1 beta Protein (Catalog#70018-DNAE)
PreparationProduced in rabbits immunized with purified, recombinant Canine IL-1 beta (Catalog#70018-DNAE; Q28292; Ala115-Ser266). IL-1 beta specific IgG was purified by Canine IL-1 beta affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Background Information

Full Nameinterleukin 1, beta
DescriptionInterleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
Research Areas
  • Neuroinflammation
Related Pathways
  • IL1 signaling pathway
Tags
  • Cancer Immunotherapy
  • Immune Checkpoint
  • Immunotherapy
  • Targeted Therapy
References
  1. Kim SH, et al. (2008) Association of -31TC and -511 CT polymorphisms in the interleukin 1 beta (IL1B) promoter in Korean keratoconus patients. Mol Vis. 14:2109-16.
  2. Wang ZC, et al. (2002) T helper 1-type immunity to trophoblast antigens in women with a history of recurrent pregnancy loss is associated with polymorphism of the IL1B promoter region. Genes Immun. 3(1): 38-42.
  3. Mattuzzi S, et al. (2007) Association of polymorphisms in the IL1B and IL2 genes with susceptibility and severity of systemic sclerosis. J Rheumatol. 34(5): 997-1004.

title: KunMingShanHaiTang formula reprograms macrophage metabolism and promotes M2 polarization via the HIF-1α pathway to alleviate ulcerative colitis symptoms in a rat model.
authors: Zhiyun Zhang; Zhen Wang; ...; XiNan Shi
journal: Journal of bioenergetics and biomembranes
date: 2025-04-02
pmid: 40172736
cited_by_count: 2
techniques: Cell Culture; Lysis; Molecular Weight; Over Expression; Plasmid Preparation; Staining
bioz_score: 93

Reviews

Write Your Own Review
You're reviewing:Anti-IL-1 beta Antibody, Rabbit Polyclonal sinobiological 70018-T16
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.