Anti-IL1RAPL2 Antibody, Rabbit Polyclonal sinobiological 10156-T16

$243.00
In stock
SKU
10156-T16
Catalog No.SizePrice (USD)
10156-T16-100100 µL$251.64

General Information

Product nameAnti-IL1RAPL2 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman IL1RAPL2
ImmunogenRecombinant Human IL1RAPL2 Protein (Catalog#10156-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human IL1RAPL2 (rh IL1RAPL2; Catalog#10156-H08H; NP_059112.1; Met1-Glu356). IL1RAPL2 specific IgG was purified by Human IL1RAPL2 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-IL-1R9 Antibody; Anti-IL1R9 Antibody; Anti-IL1RAPL-2 Antibody; Anti-TIGIRR-1 Antibody

Background Information

Full Nameinterleukin 1 receptor accessory protein-like 2
DescriptionX-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in the fetal brain and is highly homologous to IL1RAPL, which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptors are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci, and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.
References
  1. Jin H, et al . (2000) Two novel members of the interleukin-1 receptor gene family, one deleted in Xp22.1-Xp21.3 mental retardation. Eur J Hum Genet. 8(2): 87-94.
  2. Sana TR, et al . (2000) Computational identification, cloning, and characterization of IL-1R9, a novel interleukin-1 receptor-like gene encoded over an unusually large interval of human chromosome Xq22.2-q22.3. Genomics. 69(2): 252-62.
  3. Gambino F, et al . (2007) IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca 2+ -channel and neurite elongation. Proc Natl Acad Sci. 104(21): 9063-8.

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