| Catalog No. | Size | Price (USD) |
| 10943-T48-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-IL-13 R alpha 1/IL13RA1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IL-13 R alpha 1/IL13RA1 |
| Immunogen | Recombinant Human IL-13 R alpha 1/IL13RA1 Protein (Catalog#10943-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human IL-13 R alpha 1/IL13RA1 (rh IL-13 R alpha 1/IL13RA1; Catalog#10943-H08H; NP_001551.1; Met1-Thr343). IL-13 R alpha 1/IL13RA1 specific IgG was purified by Human IL-13 R alpha 1/IL13RA1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD213A1 Antibody; Anti-CT19 Antibody; Anti-IL-13Ra Antibody; Anti-IL13R Antibody; Anti-IL13RA Antibody; Anti-IL13RA1 Antibody; Anti-NR4 Antibody
Image / Experimental Information
| Image 1 Description | Anti-IL-13 R alpha 1/IL13RA1 rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: A549 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:47 kDa |
| Image 1 Alt Text | Human IL-13 R alpha 1/IL13RA1 Western blot (WB) 41221 |
| Image 1 URL | Source image |
Background Information
| Full Name | interleukin 13 receptor, alpha 1 |
| Description | Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
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