Anti-IMPA1 Antibody, Rabbit Polyclonal sinobiological 201277-T44

$143.00
In stock
SKU
201277-T44
Catalog No.SizePrice (USD)
201277-T44-5050 µL$147.96
201277-T44-100100 µL$251.64
201277-T44-200200 µL$355.32

General Information

Product nameAnti-IMPA1 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IHC-P (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman IMPA1
ImmunogenE. coli-derived Human IMPA1 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human IMPA1 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-IMP Antibody; Anti-IMPA Antibody; Anti-MRT59 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-IMPA1 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:30 kDa Observed band size:30 kDa
Image 1 Alt TextHuman IMPA1 Western blot (WB) 29412
Image 1 URLSource image
Image 2 DescriptionAnti-IMPA1 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:30 kDa Observed band size:30 kDa
Image 2 Alt TextHuman IMPA1 Immunohistochemistry(IHC) 29413
Image 2 URLSource image
Image 3 DescriptionAnti-IMPA1 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:30 kDa Observed band size:30 kDa
Image 3 Alt TextHuman IMPA1 Immunoprecipitation(IP) 29414
Image 3 URLSource image

Background Information

Full Nameinositol(myo)-1(or 4)-monophosphatase 1
DescriptionIMPA1 (Inositol Monophosphatase 1) is a Protein Coding gene. This gene encodes an enzyme that dephosphorylates Myo-inositol monophosphate to generate free Myo-inositol, a precursor of phosphatidylinositol, and is, therefore, an important modulator of intracellular signal transduction via the production of the second messenger's myoinositol 1,4,5-trisphosphate and diacylglycerol. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Additionally, IMPA1 is the main target of lithium, a drug that is at the forefront of treatment for bipolar disorder. IMPA1 is widely expressed in the testis, thyroid, and other tissues. Diseases associated with IMPA1 include Mental Retardation, Autosomal Recessive 59, and Bipolar Disorder.
Research Areas
  • Phosphatases and Regulators
Related Pathways
  • G Protein-coupled Receptors Signaling
  • MAPK-Erk Pathway

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