Anti-METAP1 Antibody, Rabbit Polyclonal sinobiological 10241-T48
$243.00
In stock
SKU
10241-T48
| Catalog No. | Size | Price (USD) |
| 10241-T48-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-METAP1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human METAP1 |
| Immunogen | Recombinant Human METAP1 Protein (Catalog#10241-H08B) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human METAP1 (rh METAP1; Catalog#10241-H08B; NP_055958.2; His52-Phe386). METAP1 specific IgG was purified by Human METAP1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-KIAA0094 Antibody; Anti-MAP1A Antibody; Anti-MetAP1A Antibody
Image / Experimental Information
| Image 1 Description | Anti-METAP1 rabbit polyclonal antibody at 1:500 dilution Lane A: A549 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:43 kDa Observed band size:43 kDa |
| Image 1 Alt Text | Human METAP1 Western blot (WB) 42204 |
| Image 1 URL | Source image |
Background Information
| Full Name | methionyl aminopeptidase 1 |
| Description | Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents. |
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