Anti-MMP-8 Antibody, Rabbit Polyclonal sinobiological 50493-T56
$243.00
In stock
SKU
50493-T56
| Catalog No. | Size | Price (USD) |
| 50493-T56-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-MMP-8 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse MMP-8 |
| Immunogen | Recombinant Mouse MMP-8 Protein (Catalog#50493-M08S) |
| Preparation | Produced in rabbits immunized with purified, recombinant Mouse MMP-8 (rM MMP-8; Catalog#50493-M08S; NP_032637.3; Met1-Ser465). MMP-8 specific IgG was purified by Mouse MMP-8 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Mmp8 Antibody
Image / Experimental Information
| Image 1 Description | Anti-MMP8 rabbit polyclonal antibody at 1:500 dilution Lane A: NIH-3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:53 kDa |
| Image 1 Alt Text | Mouse MMP-8 Western blot (WB) 41218 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-MMP8 rabbit polyclonal antibody at 1:500 dilution Lane A: NIH-3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:53 kDa |
| Image 2 Alt Text | Mouse MMP-8 Immunohistochemistry(IHC) 41219 |
| Image 2 URL | Source image |
| Image 3 Description | Anti-MMP8 rabbit polyclonal antibody at 1:500 dilution Lane A: NIH-3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:53 kDa |
| Image 3 Alt Text | Mouse MMP-8 Immunohistochemistry(IHC) 41220 |
| Image 3 URL | Source image |
Background Information
| Full Name | matrix metallopeptidase 8 |
| Description | Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects. |
| References |
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