| Catalog No. | Size | Price (USD) |
| 106449-T32-50 | 50 µL | $147.96 |
| 106449-T32-100 | 100 µL | $251.64 |
| 106449-T32-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Annexin VI/ANXA6 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse Rat (Species predicted to react based on 100% sequence homology) |
| Immunogen | A synthetic peptide corresponding to the center region of the Mouse Annexin VI/ANXA6 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Mouse Annexin VI/ANXA6, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Anx6 Antibody; Anti-Anxa6 Antibody; Anti-AnxVI Antibody; Anti-Cabm Antibody; Anti-Camb Antibody
Image / Experimental Information
| Image 1 Description | Anti-ANXA6 rabbit polyclonal antibody at 1:500 dilution Lane A: NIH-3T3 Whole Cell Lysate Lane B: Mouse Spleen tissue lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:76 kDa Observed band size:72 kDa |
| Image 1 Alt Text | Mouse Annexin VI/ANXA6 Western blot (WB) 18950 |
| Image 1 URL | Source image |
Background Information
| Full Name | annexin A6 |
| Description | Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca -dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 6 is phosphorylated in vivo associated with cell growth. Annexin 6 was not phosphorylated in quiescent cells, but was phosphorylated on serine and to a lesser extent threonine, several hours following cell stimulation. Experiment has revealed the presence of annexin A6 on the cell surface of variety cells as putative receptors and / or binding proteins for chondroitin sulfate proteoglycans, helping cells to bind with this extracellular matrix glycosaminoglycan chondroitin sulfate which is related to the cell-substratum adhesion. A post-tranlational modification other than direct protein phosphorylation may influence the activity of annexin6 and provide evidence linking cell growth with regulation of annexin 6 function. |
| References |
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