| Catalog No. | Size | Price (USD) |
| 50083-R114-20 | 20 µL | $118.49 |
| 50083-R114-50 | 50 µL | $222.17 |
| 50083-R114-100 | 100 µL | $370.28 |
General Information
| Product name | Recombinant Anti-ASGR1 Antibody, Rabbit Monoclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse ASGR1 |
| Immunogen | Recombinant Mouse ASGPR1 / ASGR1 protein (Catalog#50083-M07H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ASGPR1 / ASGR1 (rM ASGPR1 / ASGR1; Catalog#50083-M07H; NP_033844.1; Ser60-Asn284). |
| Source | Monoclonal Rabbit IgG Clone #114 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ASGPR1 Antibody; Anti-Asgr Antibody; Anti-Asgr-1 Antibody; Anti-Asgr1 Antibody; Anti-HL-1 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of mouse ASGR1 in mouse liver with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Mouse ASGPR1 Immunohistochemistry(IHC) 3384 |
| Image 1 URL | Source image |
Background Information
| Full Name | asialoglycoprotein receptor 1 |
| Description | The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The research regarded that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development. |
| References |
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title: Long-read sequencing quantifies synthetic mRNA abundance, integrity and host response in vivo
authors: McLeod Victoria M.; Yuen Daniel; ...; Johnston Angus P.R.
journal: bioRxiv
date: 2026-08-15
doi: 10.64898/2026.08.10.741180
cited_by_count: 0
techniques: Immunohistochemistry; Incubation
bioz_score: 94
title: Genome-scale CRISPR screening in a single mouse liver
authors: Heather R. Keys; Kristin A. Knouse
journal: Cell Genomics
date: 2022-12-30
pmcid: 9835819
cited_by_count: 0
techniques: Amplification; CRISPR; Clone Assay; Knock-Out; Plasmid Preparation; RNA Sequencing Assay; Recombinant; Sequencing; Software
bioz_score: 91
title: Mechanisms of anti-GPIbα antibody–induced thrombocytopenia in mice
authors: Yosuke Morodomi; Sachiko Kanaji; ...; Taisuke Kanaji
journal: Blood
date: 2021-06-18
pmid: 32157300
doi: 10.1182/blood.2019003770
pmcid: 7316218
cited_by_count: 25
techniques: Confocal Microscopy; IV Injection; Immunofluorescence; Injection; Microscopy; Purification; Software; Staining
bioz_score: 91
title: A genome-wide screen in the mouse liver reveals sex-specific and cell non-autonomous regulation of cell fitness
authors: Keys Heather R.; Knouse Kristin A.
journal: bioRxiv
date: 2021-02-01
doi: 10.1101/2021.01.30.428976
cited_by_count: 3
techniques: Antibody Labeling; Blocking Assay; Immunostaining; Incubation
bioz_score: 94
title: Our Microbial Signatures
authors: Prabha Desikan
journal: Indian journal of medical microbiology
date: 2017-10-01
doi: 10.4103/ijmm.ijmm_17_250
cited_by_count: 1
bioz_score: 91
