| Catalog No. | Size | Price (USD) |
| 50014-R012-50 | 50 µL | $177.58 |
| 50014-R012-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-carbonic anhydrase XII/CA12 Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse carbonic anhydrase XII/CA12 |
| Immunogen | Recombinant Mouse Carbonic Anhydrase XII / CA12 Protein (Catalog#50014-M08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carbonic Anhydrase XII / CA12 (rM Carbonic Anhydrase XII / CA12; Catalog#50014-M08H; NP_848483.2; Met 1-Ser 301). |
| Source | Monoclonal Rabbit IgG Clone #012 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Ca12 Antibody; Anti-Car12 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of mouse CA12 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Mouse Carbonic Anhydrase XII Immunohistochemistry(IHC) 3377 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of mouse CA12 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Image 2 Alt Text | Mouse Carbonic Anhydrase XII Immunohistochemistry(IHC) 3378 |
| Image 2 URL | Source image |
Background Information
| Full Name | carbonic anhydrase XII |
| Description | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity. |
| References |
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