| Catalog No. | Size | Price (USD) |
| 50005-R311-F-25 | 25 Tests | $133.30 |
| 50005-R311-F-100 | 100 Tests | $266.60 |
General Information
| Product name | Recombinant Anti-CD166/ALCAM Antibody (FITC), Rabbit Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse CD166/ALCAM |
| Immunogen | Recombinant Mouse CD166 / ALCAM protein (Catalog#50005-M08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD166 / ALCAM (rM CD166 / ALCAM; Catalog#50005-M08H; NP_033785.1; Met1-Lys527) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Source | Monoclonal Rabbit IgG Clone #311 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Concentration | 10 μl/Test, 0.1 mg/ml |
| Conjugate | FITC |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Synonyms: Anti-Alcam Antibody; Anti-BEN Antibody; Anti-CD166 Antibody; Anti-DM-GRASP Antibody; Anti-MuSC Antibody; Anti-SC1 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of Mouse ALCAM(CD166) expression on mouse splenocytes. BABL/c splenocytes were stained with FITC-conjugated anti-Mouse ALCAM(CD166). The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Image 1 Alt Text | Mouse CD166 / ALCAM Flow Cytometry (FC) 26252 |
| Image 1 URL | Source image |
Background Information
| Full Name | activated leukocyte cell adhesion molecule |
| Description | Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocytes. The extracellular domain of ALCAM contains five Ig-like domains (three Ig-like C2-type domains and two Ig-like V-type domains), of which the amino-terminal V1 domain is essential for ligand binding and ALCAM-mediated cell aggregation. ALCAM mediates both heterophilic (ALCAM-CD6) and homophilic (ALCAM-ALCAM) cell-cell interactions. ALCAM/CD6 interaction plays a role in T cell development and T cell regulation, as well as in the binding of T- and B-cells to activated leukocytes. Recently, homophilic (ALCAM-ALCAM) adhesion was shown to play important roles in tight cell-to-cell interaction and regulation of stem cell differentiation. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells involved in dynamic growth and/or migration, including neural development, branching organ development, hematopoiesis, immune response and tumor progression. And CD166 is regarded as a potential novel breast cancer indicator and therapeutic target. |
| References |
|
title: Step-Ladder Bioprinting to Align Collagen Fibers for Anisotropic Tissue Fabrication.
authors: Ilayda Namli; Yogendra Pratap Singh; ...; Ibrahim T Ozbolat
journal: Small (Weinheim an Der Bergstrasse, Germany)
date: 2026-01-08
pmid: 41503892
doi: 10.1002/smll.202510498
cited_by_count: 0
bioz_score: 94
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