Recombinant Anti-CD48 Antibody, Rabbit Monoclonal sinobiological 50415-R405

$1,900.00
In stock
SKU
50415-R405
Catalog No.SizePrice (USD)
50415-R405-11 mL$1,969.87
50415-R405-2020 µL$118.49
50415-R405-5050 µL$177.58
50415-R405-100100 µL$340.51

General Information

Product nameRecombinant Anti-CD48 Antibody, Rabbit Monoclonal
Validated applicationsELISA(Cap) (FAQ Protocol)
Species reactivityReacts with: Mouse
SpecificityMouse CD48
ImmunogenRecombinant Mouse CD48 / Blast-1 Protein (Catalog#50415-M08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD48 / Blast-1 (rM CD48 / Blast-1; Catalog#50415-M08H; NP_031675.1; Met1-Arg216).
SourceMonoclonal Rabbit IgG Clone #405
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-Bcm-1 Antibody; Anti-BCM1 Antibody; Anti-BLAST Antibody; Anti-BLAST-1 Antibody; Anti-BLAST1 Antibody; Anti-Cd48 Antibody; Anti-MEM-102 Antibody; Anti-Sgp-60 Antibody; Anti-SLAMF2 Antibody

Background Information

Full NameCD48 molecule
DescriptionCluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
Research Areas
  • Cancer Drug Targets
Tags
  • Cancer Immunotherapy
  • Co-inhibitory Immune Checkpoint Targets
  • Immune Checkpoint
  • Immune Checkpoint Detection: Antibodies
  • Immune Checkpoint Detection: ELISA Antibodies
  • Immune Checkpoint Detection: FCM Antibodies
  • Immune Checkpoint Detection: ICC Antibodies
  • Immune Checkpoint Detection: IHC Antibodies
  • Immune Checkpoint Detection: IP Antibodies
  • Immune Checkpoint Detection: WB Antibodies
  • Immune Checkpoint Proteins
  • Immune Checkpoint Targets
  • Immunotherapy
  • Targeted Therapy
References
  1. Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  2. Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.

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