Recombinant Anti-Fetuin B Antibody, Rabbit Monoclonal
Validated applications
ELISA (FAQ Protocol)
Species reactivity
Reacts with: Mouse
Specificity
Mouse Fetuin B No cross-reactivity in ELISA with Human FETUB
Immunogen
Recombinant Mouse Fetuin-B / FETUB protein (Catalog#50572-M08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Fetuin-B / FETUB (rM Fetuin-B / FETUB; Catalog#50572-M08H; Q9QXC1-1; Met 1-Pro 388).
Source
Monoclonal Rabbit IgG Clone #110
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Fetuin-B, also known as Fetuin-like protein IRL685 and FETUB, is a secreted protein which belongs to thefetuin family. Fetuin-B / FETUB contains twocystatin domains. Fetuin-B is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption. Fetuin-A has been identified as a major protein during fetal life and is also involved in important functions such as protease inhibitory activities and development-associated regulation of calcium metabolism and osteogenesis. Fetuin-A is a key partner in the recovery phase of an acute inflammatory response. Fetuin-B / FETUB is found at least in human and rodents. It is unambiguously a paralogue of Fetuin-A. Fetuin-A and Fetuin-B exhibit significant differences at the amino acid sequence level, notably including variations with respect to the archetypal fetuin-specific signature.
References
Olivier E., et al., 2000, Biochem. J. 350:589-97
Liu T., et al., 2005, J. Proteome Res. 4:2070-80.
Hsu SJ, et al., 2005, Genome. 47 (5): 931-46.
Liu T, et al., 2006, J. Proteome Res.4 (6): 2070-80.