Anti-IL-5 Antibody, Rabbit Polyclonal sinobiological 51068-RP01

$143.00
In stock
SKU
51068-RP01
Catalog No.SizePrice (USD)
51068-RP01-100100 µL$147.96
51068-RP01-200200 µL$251.64
51068-RP01-400400 µL$355.32

General Information

Product nameAnti-IL-5 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Mouse
SpecificityMouse IL-5
ImmunogenRecombinant Mouse IL-5 / IL5 / Interleukin 5 Protein (Catalog#51068-M08B)
PreparationProduced in rabbits immunized with purified, recombinant Mouse IL-5 / IL5 / Interleukin 5 (rM IL-5 / IL5 / Interleukin 5; Catalog#51068-M08B; P04401; Met1-Gly133). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-Il-5 Antibody; Anti-Il5 Antibody

Background Information

Full Nameinterleukin 5
DescriptionInterleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.
References
  1. Milburn MV, et al. (1993) A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5. Nature. 363(6425): 172-176.
  2. Lee JS, et al. (1989) The IL-4 and IL-5 genes are closely linked and are part of a cytokine gene cluster on mouse chromosome 11. Somat Cell Mol Genet. 15(2): 143-152.
  3. Woodcock JM, et al. (1994) Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. EMBO J. 13 (21): 5176-85.

Reviews

Write Your Own Review
You're reviewing:Anti-IL-5 Antibody, Rabbit Polyclonal sinobiological 51068-RP01
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.