| Catalog No. | Size | Price (USD) |
| 51071-T24-50 | 50 µL | $147.96 |
| 51071-T24-100 | 100 µL | $251.64 |
| 51071-T24-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-IL-36 beta/IL-1 F8 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse IL-36 beta/IL-1 F8 |
| Immunogen | Recombinant Mouse IL36B/IL1F8 Protein (Catalog#51071-MNAE) |
| Preparation | Produced in rabbits immunized with purified, recombinant Mouse IL36B/IL1F8 (rM IL36B/IL1F8; Catalog#51071-MNAE; Q9D6Z6; Met1-Lys183). IL36B/IL1F8 specific IgG was purified by Mouse IL36B/IL1F8 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-2310043N20Rik Antibody; Anti-Fil1e Antibody; Anti-If36b Antibody; Anti-Il1f8 Antibody; Anti-Il36b Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of mouse IL1F8 in mouse small intestine with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Mouse IL36B/IL1F8 Immunohistochemistry(IHC) 17783 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of mouse IL1F8 in mouse small intestine with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Image 2 Alt Text | Mouse IL36B/IL1F8 Immunohistochemistry(IHC) 17784 |
| Image 2 URL | Source image |
Background Information
| Full Name | interleukin 36, beta |
| Description | Interleukin-1 family member 8(IL1F8) also known as IL36B, is a member of the interleukin 1(IL-1) cytokine family. IL1F8 may contain a 12-stranded beta-trefoil structure. Until recently, the IL-1 family of cytokines includes four members, with three having pro-inflammatory effects such as IL1F8 and the fourth member being an IL-1 receptor antagonist (IL-1Ra). IL-1 family members exert their effects through binding to receptors that belong to the IL-1 receptor (IL-1R) family. IL1F8 exerts proinflammatory effects in primary human joint cells. Joint and serum IL-1F8 protein levels did not correlate with inflammation, but they were high in some human serum samples tested, including samples from patients with rheumatoid arthritis. IL1F8 also activated NK-κB. |
| Related Pathways |
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| References |
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