Produced in rabbits immunized with E. coli-derived Human MRPL52 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Synonyms: Anti-mL52 Antibody
Image / Experimental Information
Image 1 Description
Immunochemical staining of human MRPL52 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Mitochondrial ribosomal proteins (MRPs) are essential components for the structural and functional integrity of the mitoribosome complex. Throughout evolution, the mammalian mitoribosome has acquired new Mrp genes to compensate for loss of ribosomal RNA. More than 80 MRPs have been identified in mammals. Mrp genes are not a gene family descended from a single ancestral gene, and that each MRP has a unique and essential role in the mitoribosome complex. The MRPL52 gene encodes a 39S subunit protein that has no bacterial homolog. Multiple transcript variants encoding different protein isoforms were identified through sequence analysis.
References
Cheong A, et al. (2020) Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns 38 119147.