Anti-MMAE Mouse mAb _ 31903ES yeasen
$395.00
In stock
SKU
31903ES60
Product Description
MMAE, or monomethyl auristatin E, is a potent cytotoxic agent commonly used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It is an antimitotic agent which inhibits cell division by blocking the polymerization of tubulin.
Specifications
| Source | Monoclonal anti-MMAE antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAE. |
| Host | Mouse |
| Purity | ＞ 94% as determined by reduced SDS-PAGE ＞ 97% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC |
| Concentration | 1 mg/mL |
| Buffer | 1×PBS, pH7.4. Type Monoclonal Antibody |
| Cat.No. | 31903ES60/31903ES80 |
| Size | 100 μg/1 mg |
| Isotype | IgG 1 |
| Activity | EC 50 =6.3 ng/mL by ELISA |
Applications
- ELISA
Storage
This product should be stored at -25~-15℃ for one year, do not freeze.
Notes
This product is for research use only. Please operate with lab coats and disposable gloves, for your safety. Data SDS-PAGE Anti-MMAE mouse mAb on SDS-PAGE under reduced condition. The purity is 94.7% Anti-MMAE mouse mAb on SDS-PAGE under non-reduced condition. The purity is 97.6%. S EC-HPLC The purity of Anti-MMAE mouse mAb is 98% as determined by SEC-HPLC. ELISA Data Dose response curve shows that the EC 50 of Anti-MMAE mouse mAb is 6.3 n g/mL.
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