Recombinant Human IL-23 Protein _ 90225ES yeasen
$140.00
In stock
SKU
90225ES10
Product Description
Interleukin-23 (IL-23) is a pro-inflammatory heterodimeric protein consisting of two subunits: a unique p19 subunit and a p40 subunit shared with IL-12.IL-23 is secreted by activated dendritic cells and macrophages and signals through the receptor for IL-23R in complex with IL-12Rβ 1. IL-23 has been shown to enhance the proliferation of memory T cells. It also stimulates IFN-γ production in NK cells, induces IL-17 production, and drives Th17-mediated responses. This Recombinant Human IL-23 is supplied in liquid form, highly active, highly pure, low endotoxin, and label free.
Specifications
| Synonyms | Interleukin-23 IL23 |
| Source | HEK293 |
| Source | Human IL-23 p40 （ Ile23-Ser328 ） &Human IL-23 p19 (Arg20-Pro189) |
| Tag | Not Physical Appearance F luids |
| Molecular Weight | Predicted Moleucular weight: 36.5 kDa (p40) & 18.5 kDa (p19) |
| Purity | > 95% determined by SDS-PAGE. Biological Activity Measured by its ability to induce IL-17 secretion by mouse splenocytes.The EC50 for this effect is 0.25 pg/mL. |
| Concentration | 0.2 mg/mL |
| Formulation | Dissolved in sterile PBS buffer. |
| Endotoxin | < 0.01 EU/μg by the LAL method. |
| Accession | p40 （ P29460 ） & p19 （ AAG37232 ） |
Storage
-85~-65℃ storage, valid for 1 year after receipt. Avoid repeated freezing and thawing, centrifuge before opening the vial. It is recommended to aliquot for one experimental use, after aliquoting, freeze at -80℃. Cautions 1. Please operate with lab coats and disposable gloves,for your safety. 2 . This product is for research use only.
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