Description
Recombinant Human Leucine-rich Alpha-2-glycoprotein is produced by our Mammalian expression system and the target gene encoding Val36-Gln347 is expressed with a human IgG1 Fc, 6His tag at the C-terminus.
Product Details
| Item | Details |
| Known As | Leucine-rich alpha-2-glycoprotein; LRG and LRG1 |
| Mol Mass | 62.3 KDa |
| APMol Mass | 65-90 KDa, reducing conditions |
| Formulation Description | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 10% Glycerol, pH 8.0. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| Shipping | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Background
LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid.
title: A New Approach for the Diagnosis of Myelodysplastic Syndrome Subtypes Based on Protein Interaction Analysis
authors: Chrastinová Leona, Pastva Ondřej, Bocková Markéta, Lynn Nicholas S., Šácha Pavel, Hubálek Martin, Suttnar Jiří, Kotlín Roman, Štikarová Jana, Hlaváčková Alžběta, Pimková Kristýna, Čermák Jaroslav, Homola Jiří, Dyr Jan E.
date: 2019
journal: Scientific Reports
MDSD