NLRC3 Polyclonal antibody 30455-1-AP proteintech
$149.00
In stock
SKU
30455-1-AP
| Catalog Number | 30455-1-AP |
| Synonyms | CARD15 like protein, Caterpiller protein 16.2, CLR16.2, FLJ00348, NLRC3, NOD3, Protein NLRC3 |
| Host | Rabbit |
| Reactivity | Human |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Daudi cells, Jurkat cells, Raji cells, Ramos cells |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:4000 |
| Positive WB detected in | Daudi cells, Jurkat cells, Raji cells, Ramos cells |
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Tested Reactivity | Human |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag32323 Product name: Recombinant human NLRC3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-130 aa of NM_178844 Sequence: MRKQEVRTGREAGQGHGTGSPAEQVKALMDLLAGKGSQGSQAPQALDRTPDAPLGPCSNDSRIQRHRKALLSKVGGGPELGGPWHRLASLLLVEGLTDLQLREHDFTQVEATRGGGHPARTVALDRLFLP Predict reactive species |
| Full Name | NLR family, CARD domain containing 3 |
| Calculated Molecular Weight | 115 kDa |
| Observed Molecular Weight | 100-110 kDa |
| GenBank Accession Number | NM_178844 |
| Gene Symbol | NLRC3 |
| Gene ID (NCBI) | 197358 |
| RRID | AB_3086322 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q7RTR2 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for NLRC3 antibody 30455-1-AP | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:4000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells. In macrophages, NLRC3 inhibits the activation of the NF-κB signaling pathway, the STING/TBK1 signaling pathway, and the formation of the inflammasome. In the context of T cells immune response, NLRC3 prevents the activation of T cells by regulating the function of dendritic cells and directly influencing the function of T cells. Protocols Product Specific Protocols WB protocol for NLRC3 antibody 30455-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
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