Human CALML5 ELISA Kit sinobiological KIT11783

$714.00
In stock
SKU
KIT11783
Catalog No.SizePrice (USD)
KIT11783-11 Kit (96 Tests)$740.55

General Information

Product nameHuman CALML5 ELISA Kit
SpecificityThis assay recognizes recombinant human CALML5.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeRecombinant protein
Sensitivity4.57 pg/mL
Assay range23.44-1500 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution
Product overviewThis Human CALML5 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human CALML5 protein in Recombinant protein . It contains recombinant Human CALML5, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of PLK1 at 15 ng/mL in a mid-range recombinant human CALML5 control were assayed for interference. No significant interference was observed.

Synonyms: CLSP ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman CALML5 ELISA Kit Standard Curve 109
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman CALML5 ELISA Kit Specificity 159
Image 2 URLSource image

Background Information

Full Namecalmodulin like 5
DescriptionCalmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain.
Related Pathways
  • Actin Dynamics Signaling Pathway
  • B Cell Receptor Signaling Pathway
  • T Cell Receptor Signaling Pathway
References
  1. Mehul B., et al., 2000, J. Biol. Chem. 275:12841-12847.
  2. Babini E., et al., 2006, Structure 14:1029-1038.
  3. Kawabata,K. et al., 2007, Gene Ther. 14 (16):1199-207.

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