Anti-CD200R Antibody, Rabbit Polyclonal sinobiological 11218-T52

$143.00
In stock
SKU
11218-T52
Catalog No.SizePrice (USD)
11218-T52-5050 µL$147.96
11218-T52-100100 µL$251.64
11218-T52-200200 µL$355.32

General Information

Product nameAnti-CD200R Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), ELISA (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD200R
ImmunogenRecombinant Human CD200R1 protein (Catalog#11218-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human CD200R1 (rh CD200R1; Catalog#11218-H08H; AAI43394.1; Met1-Leu266). CD200R1 specific IgG was purified by Human CD200R1 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CD200R Antibody; Anti-CRTR2 Antibody; Anti-HCRTR2 Antibody; Anti-MOX2R Antibody; Anti-OX2R Antibody; Anti-UNQ2522/PRO6015 Antibody

Image / Experimental Information

Image 1 DescriptionCD200R1 was immunoprecipitated using: Lane A:0.5 mg 293T Whole Cell Lysate Lane B:0.5 mg K562 Whole Cell Lysate 0.5 µL anti-CD200R1 rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-CD200R1 rabbit polyclonal antibody,at 1:1000 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 37 kDa Observed band size: 37 kDa
Image 1 Alt TextHuman CD200R1 Immunoprecipitation(IP) 8071
Image 1 URLSource image
Image 2 DescriptionCD200R1 was immunoprecipitated using: Lane A:0.5 mg 293T Whole Cell Lysate Lane B:0.5 mg K562 Whole Cell Lysate 0.5 µL anti-CD200R1 rabbit polyclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-CD200R1 rabbit polyclonal antibody,at 1:1000 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 37 kDa Observed band size: 37 kDa
Image 2 Alt TextHuman CD200R1 Western blot (WB) 13370
Image 2 URLSource image

Background Information

Full NameCD200 receptor 1
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cell surface glycoprotein CD200 receptor 1 (CD200R1) is an isoform of CD200 receptors that is expressed on cells of the myeloid lineage. CD200R1 is a receptor for the OX-2 membrane glycoprotein. The receptor-substrate interaction may serve as a myeloid downregulatory signal.
Research Areas
  • Neuroinflammation
  • Cancer Drug Targets
Tags
  • Cancer Immunotherapy
  • Immune Checkpoint
  • Immunotherapy
  • Targeted Therapy
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

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