Human HER3/ERBB3 ELISA Kit sinobiological KIT10201
$400.00
In stock
SKU
KIT10201
| Catalog No. | Size | Price (USD) |
| KIT10201-1 | 1 Kit (96 Tests) | $414.71 |
General Information
| Product name | Human HER3/ERBB3 ELISA Kit |
| Specificity | This assay recognizes both recombinant and natural Human ErbB3. |
| Conjugate | HRP |
| Shipping | This ELISA Kit is shipped at ambient temperature. |
| Storage | Unopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA |
| Assay type | Solid Phase Sandwich ELISA (quantitative) |
| Sample type | Serum |
| Sensitivity | 26.79 pg/mL |
| Assay range | 31.25-2000 pg/mL |
| Materials provided | 1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Color Reagent A 7. Color Reagent B 8. Stop Solution |
| Product overview | This Human HER3/ERBB3 ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human HER3/ERBB3 protein in Serum . It contains recombinant Human HER3/ERBB3, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use. |
| Interference | Preparations of human EGFR, ErbB2 and ErbB4 at 18 ng/mL in a mid-range recombinant human ErbB3 control were assayed for interference. No significant interference was observed. |
Synonyms: c-erbB-3 ELISA Kit, Human; c-erbB3 ELISA Kit, Human; ErbB-3 ELISA Kit, Human; erbB3-S ELISA Kit, Human; FERLK ELISA Kit, Human; HER3 ELISA Kit, Human; LCCS2 ELISA Kit, Human; MDA-BF-1 ELISA Kit, Human; p180-ErbB3 ELISA Kit, Human; p45-sErbB3 ELISA Kit, Human; p85-sErbB3 ELISA Kit, Human; VSCN1 ELISA Kit, Human
Image / Experimental Information
| Image 1 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 1 Alt Text | Human EEBB3/HER3 ELISA Kit Standard Curve 15926 |
| Image 1 URL | Source image |
| Image 2 Description | This standard curve is only for demonstration purposes. A standard curve should be generated for each assay. |
| Image 2 Alt Text | Human EEBB3/HER3 ELISA Kit Specificity 15935 |
| Image 2 URL | Source image |
Background Information
| Full Name | erb-b2 receptor tyrosine kinase 3 |
| Description | ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form. |
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