Human KLK3/PSA ELISA Kit sinobiological KIT10771

$400.00
In stock
SKU
KIT10771
Catalog No.SizePrice (USD)
KIT10771-11 Kit (96 Tests)$414.71

General Information

Product nameHuman KLK3/PSA ELISA Kit
SpecificityThis assay recognizes both recombinant and natural Human KLK3.
ConjugateHRP
ShippingThis ELISA Kit is shipped at ambient temperature.
StorageUnopened Kit: Store at 2 - 8℃ Opened/Reconstituted Reagents: Please refer to CoA
Assay typeSolid Phase Sandwich ELISA (quantitative)
Sample typeSerum
Sensitivity16.09 pg/mL
Assay range46.88-3000 pg/mL
Materials provided1. 96 well microplate coated with Capture Antibody 2. Detection Antibody conjugated to HRP 3. Standards 4. Wash Buffer Concentrate 5. Dilution Buffer Concentrate 6. Sample Dilution Buffer Concentrate 7. Color Reagent A 8. Color Reagent B 9. Stop Solution
Product overviewThis Human KLK3/PSA ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of Human KLK3/PSA protein in Serum . It contains recombinant Human KLK3/PSA, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
InterferencePreparations of the following factors at 40 ng/mL in a mid-range recombinant Human KLK3 control were assayed for interference. No significant interference was observed.

Synonyms: APS ELISA Kit, Human; hK3 ELISA Kit, Human; KLK2A1 ELISA Kit, Human; PSA ELISA Kit, Human

Image / Experimental Information

Image 1 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 1 Alt TextHuman KLK3 ELISA Kit Standard Curve 14513
Image 1 URLSource image
Image 2 DescriptionThis standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
Image 2 Alt TextHuman KLK3 ELISA Kit Specificity 14529
Image 2 URLSource image

Background Information

Full Namekallikrein related peptidase 3
DescriptionKLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases. KLK3 contains one peptidase S1 domain. KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.
Tags
  • Cancer Immunotherapy
  • Immune Checkpoint
  • Immunotherapy
  • Targeted Therapy
References
  1. Koistinen H, et al. (2008) Development of peptides specifically modulating the activity of KLK2 and KLK3. Biol Chem. 389(6): 633-42.
  2. Yousef GM, et al. (2002) Kallikreins, steroid hormones and ovarian cancer: is there a link? Minerva Endocrinol. 27(3): 157-66.
  3. Parikh H, et al. (2011) Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels. Hum Genet. 129(6): 675-85.

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